What does targeted therapy for Atopic Eczema mean? Targeted therapy for atopic eczema is a type of treatment that uses new classes of medications to very specifically target components of the immune system that are involved in the development of eczema. This is considered as immunomodulation, as opposed to broad immunosuppression that is not specific. They are usually given by injection and can be very effective in treating moderate to severe eczema. For more information: https://www.allergyfoundation.co.za